Feline A1C (glycohemoglobin) Peer Reviewed Research for establishing normal, transitional and diabetic A1C levels

Title Journal DATE A1c Value
Glycosylated hemoglobin in the cat: affinity chromatography determination in healty, permanent diabetes mellitus and transient hyperglycemic cats Tierarztl Prax. 1995 Apr;23(2):155-61. (German Article)


By its help the reference interval for feline GHb was established from blood samples of 62 healthy cats. It ranged between 0.31 to 1.58% with a median of 0.92%. 21 newly diagnosed diabetic cats were reliably determined to be diabetic, because the GHb exceeded significantly the upper limit of the reference interval of 1.30%. The statistical difference between diabetic and healthy cats was highly significant (p < 0.00001). It was confirmed that the GHb value helps to distinguish diabetic from transient hyperglycemic cats
Diagnostic utility of glycosylated hemoglobin concentrations in
the cat
Domestic Animal Endocrinology
Volume 16, Issue 1, January 1999, Pages 11–17
1999 "It is concluded that GHb measurements are a
simple and reliable way to monitor changes in glucose control in the diabetic cat over a prolonged period."
Glycosylated hemoglobin concentration for assessment of glycemic control in diabetic cats. J Vet Intern Med. 1997 May-Jun;11(3):161-5 1997 "….blood GHb conentrations in the healthy norm-glycemic cats were 1.7%, respectively."  "…6 cats with transient diabetes emllitus 8.2 +-"  "….5 docile diabetic cats 12.2 +…."
Comparison of serum fructosamine and blood glycosylated hemoglobin concentrations for assessment of glycemic control in cats with diabetes mellitus. J Am Vet Med Assoc. 1999 Jun 15;214(12):1794-8. 1999 Serum fructosamine and blood GHb concentrations are clinically useful tools for monitoring control of glycemia in cats with diabetes mellitus. 1.6 to  1.8 A1c for normal cats, Transient or pre-diabetes 6 A1c
Long Term Monitoring of the Diabetic dog and cat Diabetes Mellitus 1995 "Normal dogs have a mean glycosylated hemoglobin of 2.95 +- 0.149, whereas pre diabetic dogs have a mean concentration of 4.97 +- 0.609"
Intensive 50-week evaluation of glipizide administration in 50 cats with previously untreated diabetes mellitus. J Am Vet Med Assoc. 1997 Mar 15;210(6):772-7. 1997 1.6 normal to 3.2 normal
The Big Pet Diabetes Survey: Perceived Frequency and Triggers for Euthanasia
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